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MCAT Question A Day - 7/15/14 - Answer!

Which of the following is the best explanation for why pancreatic enzymes are secreted in zymogen form?

A.  A delay in digestion is required in order for bile to increase the surface area chyme.
B.  Enzymes are most active in zymogen form.
C.  Zymogens will not digest bile in the pancreatic duct.
D.  Pancreatic cells are not as easily replaced as intestinal epithelium

D is correct. The best answer is D because only D is both true and reveals a benefit for enzymes to be inactive while in the pancreas. A may seem logical but would only apply to lipase. B is false. C itrue but is not an adequate explanation.

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