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MCAT Question A Day - 6/10/13 - Answer!

The rapid reabsorption of water brought about by ADH is made easier by the “countercurrent multiplier,” which involves the active transport of salts at the ascending loop of Henle. What is the result of this countercurrent multiplier effect?

A.  The filtrate becomes hypotonic while the surrounding tissues become hypertonic.
B.  The filtrate becomes hypertonic while the surrounding tissues become hypotonic.
C.  The filtrate becomes isotonic to the surrounding tissues.
D.  The tissues become isotonic to the filtrate.

The correct answer is (A). The active transport of salt from the ascending loop makes the surrounding tissues hypertonic, while leaving the filtrate hyptonic as it continues through the distal convoluted tubules and collecting ducts.